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A total of three % of Lively compound is excreted in urine as unchanged active compound. Tapentadol is Also metabolised to N-desmethyl tapentadol (13 %) by CYP2C9 and CYP2C19 and also to hydroxy tapentadol (2 %) by CYP2D6, which can be additional metabolised by conjugation. As a result, Energetic co